Summary for 6DCN
Entry DOI | 10.2210/pdb6dcn/pdb |
Related | 5VAU 5VAX 5VAY |
Descriptor | BCL-xl protein, Beclin-1 (3 entities in total) |
Functional Keywords | apoptosis, bcl-2, autophagy, beclin 1 |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 41257.78 |
Authors | Lee, E.F.,Smith, B.J.,Smith, N.A.,Yao, S.,Fairlie, W.D. (deposition date: 2018-05-07, release date: 2018-05-23, Last modification date: 2023-10-11) |
Primary citation | Lee, E.F.,Smith, N.A.,Soares da Costa, T.P.,Meftahi, N.,Yao, S.,Harris, T.J.,Tran, S.,Pettikiriarachchi, A.,Perugini, M.A.,Keizer, D.W.,Evangelista, M.,Smith, B.J.,Fairlie, W.D. Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1. Autophagy, 15:785-795, 2019 Cited by PubMed: 30626284DOI: 10.1080/15548627.2018.1564557 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.444 Å) |
Structure validation
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