6DC1

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 25 round 7

6DC1 の概要

• エントリーDOI: 10.2210/pdb6dc1/pdb
• 分子名称: Kemp eliminase KE07, 5-nitro-2-oxidanyl-benzenecarbonitrile, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
• 機能のキーワード: kemp eliminase, directed evolution, ke07, de novo protein, lyase
• 由来する生物種: synthetic construct
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 351754.60

構造登録者

Jackson, C.J.,Hong, N.-S.,Carr, P.D. (登録日: 2018-05-03, 公開日: 2018-08-01, 最終更新日: 2023-10-04)

• 主引用文献: Hong, N.S.,Petrovic, D.,Lee, R.,Gryn'ova, G.,Purg, M.,Saunders, J.,Bauer, P.,Carr, P.D.,Lin, C.Y.,Mabbitt, P.D.,Zhang, W.,Altamore, T.,Easton, C.,Coote, M.L.,Kamerlin, S.C.L.,Jackson, C.J.; The evolution of multiple active site configurations in a designed enzyme.; Nat Commun, 9:3900-3900, 2018; PubMed: 30254369; DOI: 10.1038/s41467-018-06305-y

実験手法

X-RAY DIFFRACTION (2.68 Å)