6DC0

Tribbles (TRIB1) pseudokinase fused to CCAAT-enhancer binding protein (C/EBPalpha) degron

6DC0 の概要

• エントリーDOI: 10.2210/pdb6dc0/pdb
• 分子名称: Tribbles homolog 1,CCAAT/enhancer-binding protein alpha (2 entities in total)
• 機能のキーワード: tribbles, psuedokinase, ccaat-enhancer binding protein, trb1, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 65618.95

構造登録者

Jamieson, S.A.,Brewster, J.L.,Mace, P.D. (登録日: 2018-05-03, 公開日: 2018-10-10, 最終更新日: 2023-10-04)

• 主引用文献: Jamieson, S.A.,Ruan, Z.,Burgess, A.E.,Curry, J.R.,McMillan, H.D.,Brewster, J.L.,Dunbier, A.K.,Axtman, A.D.,Kannan, N.,Mace, P.D.; Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1.; Sci Signal, 11:-, 2018; PubMed: 30254053; DOI: 10.1126/scisignal.aau0597

実験手法

X-RAY DIFFRACTION (2.8 Å)