6DB9
Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer
Summary for 6DB9
Entry DOI | 10.2210/pdb6db9/pdb |
Descriptor | RNA (60-MER), Fab-Heavy-Chain, Fab-Light-Chain, ... (5 entities in total) |
Functional Keywords | fluorescent aptamer, fab, dir, rna, rna-immune system complex, rna/immune system |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 67376.46 |
Authors | Shao, Y.,Shelke, S.A.,Laski, A.,Piccirilli, J.A. (deposition date: 2018-05-02, release date: 2018-11-14, Last modification date: 2023-10-04) |
Primary citation | Shelke, S.A.,Shao, Y.,Laski, A.,Koirala, D.,Weissman, B.P.,Fuller, J.R.,Tan, X.,Constantin, T.P.,Waggoner, A.S.,Bruchez, M.P.,Armitage, B.A.,Piccirilli, J.A. Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9:4542-4542, 2018 Cited by PubMed: 30382099DOI: 10.1038/s41467-018-06942-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.025 Å) |
Structure validation
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