6DB8

Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer

6DB8 の概要

• エントリーDOI: 10.2210/pdb6db8/pdb
• 分子名称: Fab-Heavy chain, RNA (60-MER), Fab-Light chain, ... (5 entities in total)
• 機能のキーワード: fluorescent aptamer, fab, dir, rna, rna-immune system complex, rna/immune system
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 67525.16

構造登録者

Shao, Y.,Shelke, S.A.,Laski, A.,Piccirilli, J.A. (登録日: 2018-05-02, 公開日: 2018-11-14, 最終更新日: 2023-10-04)

• 主引用文献: Shelke, S.A.,Shao, Y.,Laski, A.,Koirala, D.,Weissman, B.P.,Fuller, J.R.,Tan, X.,Constantin, T.P.,Waggoner, A.S.,Bruchez, M.P.,Armitage, B.A.,Piccirilli, J.A.; Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif.; Nat Commun, 9:4542-4542, 2018; PubMed: 30382099; DOI: 10.1038/s41467-018-06942-3

実験手法

X-RAY DIFFRACTION (1.86541345549 Å)