6DA9

Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes with FMN bound at 2.05 A resolution

Summary for 6DA9

• Entry DOI: 10.2210/pdb6da9/pdb
• Related: 6DA6 6DA7
• Descriptor: UbiD-like decarboxylase, FLAVIN MONONUCLEOTIDE, MANGANESE (II) ION, ... (6 entities in total)
• Functional Keywords: ttnd, decarboxylase, tautomycetin biosynthesis, prfmn binding, lyase, structural genomics, psi-biology, enzyme discovery for natural product biosynthesis, natpro
• Biological source: Streptomyces griseochromogenes
• Total number of polymer chains: 1
• Total formula weight: 56307.69

Authors

Han, L.,Rudolf, J.D.,Chang, C.-Y.,Miller, M.D.,Soman, J.,Xu, W.,Phillips Jr., G.N.,Shen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2018-05-01, release date: 2018-10-03, Last modification date: 2023-10-04)

• Primary citation: Annaval, T.,Han, L.,Rudolf, J.D.,Xie, G.,Yang, D.,Chang, C.Y.,Ma, M.,Crnovcic, I.,Miller, M.D.,Soman, J.,Xu, W.,Phillips Jr., G.N.,Shen, B.; Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.; ACS Chem. Biol., 13:2728-2738, 2018; PubMed: 30152678; DOI: 10.1021/acschembio.8b00673

Experimental method

X-RAY DIFFRACTION (2.05 Å)