6DA7

Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes with apo form at 1.83 A resolution (I222)

6DA7 の概要

• エントリーDOI: 10.2210/pdb6da7/pdb
• 関連するPDBエントリー: 6DA6 6DA9
• 分子名称: UbiD-like decarboxylase, SODIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total)
• 機能のキーワード: ttnd, decarboxylase, tautomycetin biosynthesis, prfmn binding, lyase, structural genomics, psi-biology, enzyme discovery for natural product biosynthesis, natpro
• 由来する生物種: Streptomyces griseochromogenes
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56702.36

構造登録者

Han, L.,Rudolf, J.D.,Chang, C.-Y.,Miller, M.D.,Soman, J.,Phillips Jr., G.N.,Shen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (登録日: 2018-05-01, 公開日: 2018-10-03, 最終更新日: 2023-10-04)

• 主引用文献: Annaval, T.,Han, L.,Rudolf, J.D.,Xie, G.,Yang, D.,Chang, C.Y.,Ma, M.,Crnovcic, I.,Miller, M.D.,Soman, J.,Xu, W.,Phillips Jr., G.N.,Shen, B.; Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway.; ACS Chem. Biol., 13:2728-2738, 2018; PubMed: 30152678; DOI: 10.1021/acschembio.8b00673

実験手法

X-RAY DIFFRACTION (1.83 Å)