6DA6

Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes, apo form at 2.6 A resolution (P212121)

Summary for 6DA6

Entry DOI	10.2210/pdb6da6/pdb
Related	6DA7 6DA9
Descriptor	UbiD-like decarboxylase, MAGNESIUM ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	ttnd, decarboxylase, tautomycetin biosynthesis, prfmn binding, lyase, structural genomics, psi-biology, enzyme discovery for natural product biosynthesis, natpro
Biological source	Streptomyces griseochromogenes
Total number of polymer chains	4
Total formula weight	220679.92
Authors	Han, L.,Rudolf, J.D.,Chang, C.-Y.,Miller, M.D.,Soman, J.,Phillips Jr., G.N.,Shen, B.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2018-05-01, release date: 2018-10-03, Last modification date: 2023-10-04)
Primary citation	Annaval, T.,Han, L.,Rudolf, J.D.,Xie, G.,Yang, D.,Chang, C.Y.,Ma, M.,Crnovcic, I.,Miller, M.D.,Soman, J.,Xu, W.,Phillips Jr., G.N.,Shen, B. Biochemical and Structural Characterization of TtnD, a Prenylated FMN-Dependent Decarboxylase from the Tautomycetin Biosynthetic Pathway. ACS Chem. Biol., 13:2728-2738, 2018 Cited by PubMed: 30152678 DOI: 10.1021/acschembio.8b00673 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation