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6D85

Structure of the Bovine p85a BH domain E217K mutant

Summary for 6D85
Entry DOI10.2210/pdb6d85/pdb
DescriptorPhosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION (3 entities in total)
Functional Keywordsgap protein, e217k mutant, signaling protein
Biological sourceBos taurus (Bovine)
Total number of polymer chains2
Total formula weight44106.61
Authors
Moore, S.A.,Marshall, J.D.,Anderson, D.H. (deposition date: 2018-04-25, release date: 2018-05-23, Last modification date: 2023-11-15)
Primary citationMellor, P.,Marshall, J.D.S.,Ruan, X.,Whitecross, D.E.,Ross, R.L.,Knowles, M.A.,Moore, S.A.,Anderson, D.H.
Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation.
Sci Rep, 8:7108-7108, 2018
Cited by
PubMed: 29740032
DOI: 10.1038/s41598-018-25487-5
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.203 Å)
Structure validation

217705

數據於2024-03-27公開中

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