6D85
Structure of the Bovine p85a BH domain E217K mutant
Summary for 6D85
Entry DOI | 10.2210/pdb6d85/pdb |
Descriptor | Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION (3 entities in total) |
Functional Keywords | gap protein, e217k mutant, signaling protein |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 2 |
Total formula weight | 44106.61 |
Authors | Moore, S.A.,Marshall, J.D.,Anderson, D.H. (deposition date: 2018-04-25, release date: 2018-05-23, Last modification date: 2023-11-15) |
Primary citation | Mellor, P.,Marshall, J.D.S.,Ruan, X.,Whitecross, D.E.,Ross, R.L.,Knowles, M.A.,Moore, S.A.,Anderson, D.H. Patient-derived mutations within the N-terminal domains of p85 alpha impact PTEN or Rab5 binding and regulation. Sci Rep, 8:7108-7108, 2018 Cited by PubMed: 29740032DOI: 10.1038/s41598-018-25487-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.203 Å) |
Structure validation
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