6D7O

Crystal Structure of Rat TRPV6* in complex with 2-Aminoethoxydiphenyl borate (2-APB)

6D7O の概要

• エントリーDOI: 10.2210/pdb6d7o/pdb
• 分子名称: Transient receptor potential cation channel subfamily V member 6, CALCIUM ION, 2-aminoethyl diphenylborinate, ... (4 entities in total)
• 機能のキーワード: ion channels, transporter, calcium channel, epithelial calcium channel, membrane protein, membrane protein-inhibitor complex, membrane protein/inhibitor
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 77612.93

構造登録者

Singh, A.K.,Saotome, K.,McGoldrick, L.L.,Sobolevsky, A.I. (登録日: 2018-04-25, 公開日: 2018-07-18, 最終更新日: 2023-10-04)

• 主引用文献: Singh, A.K.,Saotome, K.,McGoldrick, L.L.,Sobolevsky, A.I.; Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.; Nat Commun, 9:2465-2465, 2018; PubMed: 29941865; DOI: 10.1038/s41467-018-04828-y

実験手法

X-RAY DIFFRACTION (3.45 Å)