Cryo-EM structure of the zebrafish TRPM2 channel in the presence of Ca2+

Summary for 6D73

EMDB information7822
DescriptorTransient receptor potential cation channel, subfamily M, CALCIUM ION (2 entities in total)
Functional Keywordswarmth sensor, redox sensor, calcium-permeable ion channel, ion channel, transport protein
Biological sourceDanio rerio (Zebrafish)
Total number of polymer chains4
Total molecular weight670594.81
Yin, Y.,Wu, M.,Borschel, W.F.,Lander, G.C.,Lee, S.-Y. (deposition date: 2018-04-23, release date: 2019-05-15, Last modification date: 2019-07-31)
Primary citation
Yin, Y.,Wu, M.,Borschel, W.F.,Lander, G.C.,Lee, S.-Y.
Structure of the warmth- and redox-sensing ion channel TRPM2
To Be Published,
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers7 0.1% 1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report