6D64

Crystal Structure of Human CD1b in Complex with POPC

Summary for 6D64

DescriptorT-cell surface glycoprotein CD1b, Beta-2-microglobulin, N-ACETYL-D-GLUCOSAMINE, ... (13 entities in total)
Functional Keywordsbc8b, cd1, cd1b, pc, popc, phosphatidylcholine, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight50662.32
Authors
Shahine, A.E.,Rossjohn, J. (deposition date: 2018-04-20, release date: 2019-01-16)
Primary citation
Shahine, A.,Reinink, P.,Reijneveld, J.F.,Gras, S.,Holzheimer, M.,Cheng, T.Y.,Minnaard, A.J.,Altman, J.D.,Lenz, S.,Prandi, J.,Kubler-Kielb, J.,Moody, D.B.,Rossjohn, J.,Van Rhijn, I.
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10:56-56, 2019
PubMed: 30610190 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-07898-0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20980 0.3% 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6d64
no rotation
Molmil generated image of 6d64
rotated about x axis by 90°
Molmil generated image of 6d64
rotated about y axis by 90°
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