6D4O
Eubacterium eligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate
Summary for 6D4O
Entry DOI | 10.2210/pdb6d4o/pdb |
Descriptor | Beta-glucuronidase, (5aR,9aR)-2-chloro-11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5a,6,9,9a-tetrahydrodibenzo[b,f][1,4]oxazepine, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | glycosyl hydrolase, hydrolase |
Biological source | [Eubacterium] eligens |
Total number of polymer chains | 1 |
Total formula weight | 70387.50 |
Authors | Pellock, S.J.,Walton, W.G.,Redinbo, M.R. (deposition date: 2018-04-18, release date: 2018-07-25, Last modification date: 2024-03-13) |
Primary citation | Pellock, S.J.,Creekmore, B.C.,Walton, W.G.,Mehta, N.,Biernat, K.A.,Cesmat, A.P.,Ariyarathna, Y.,Dunn, Z.D.,Li, B.,Jin, J.,James, L.I.,Redinbo, M.R. Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception. ACS Cent Sci, 4:868-879, 2018 Cited by PubMed: 30062115DOI: 10.1021/acscentsci.8b00239 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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