6D0U
Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit
Summary for 6D0U
Entry DOI | 10.2210/pdb6d0u/pdb |
Descriptor | Hemagglutinin, Antibody C05 V110P/A117E mutant, heavy chain, Antibody C05, light chain, ... (4 entities in total) |
Functional Keywords | computational design, antibody, influenza, hemagglutinin, antiviral protein |
Biological source | Influenza A virus More |
Total number of polymer chains | 12 |
Total formula weight | 320980.15 |
Authors | Wu, N.C.,Wilson, I.A. (deposition date: 2018-04-11, release date: 2019-01-16, Last modification date: 2023-10-04) |
Primary citation | Sevy, A.M.,Wu, N.C.,Gilchuk, I.M.,Parrish, E.H.,Burger, S.,Yousif, D.,Nagel, M.B.M.,Schey, K.L.,Wilson, I.A.,Crowe Jr., J.E.,Meiler, J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc. Natl. Acad. Sci. U.S.A., 116:1597-1602, 2019 Cited by PubMed: 30642961DOI: 10.1073/pnas.1806004116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
Download full validation report