6CZN

Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide

Summary for 6CZN

DescriptorEstrogen receptor, GRIP Peptide, 4,4'-[(1R,2R)-1-phenylbutane-1,2-diyl]diphenol, ... (4 entities in total)
Functional Keywordsestrogen agonist, breast cancer, nuclear hormone receptor, nuclear protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total molecular weight62395.62
Authors
Fanning, S.W.,Han, R.,Maximov, P.,Jordan, V.C.,Greene, G.L. (deposition date: 2018-04-09, release date: 2019-03-20)
Primary citation
Fanning, S.W.
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.5 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.239400 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6czn
no rotation
Molmil generated image of 6czn
rotated about x axis by 90°
Molmil generated image of 6czn
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6czn
no rotation
Molmil generated image of 6czn
rotated about x axis by 90°
Molmil generated image of 6czn
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6czn.pdb1.gz [73.5 KB])
Coordinate files for Biological unit (6czn.pdb2.gz [76.82 KB])