6CZN
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Summary for 6CZN
Entry DOI | 10.2210/pdb6czn/pdb |
Descriptor | Estrogen receptor, GRIP Peptide, 4,4'-[(1R,2R)-1-phenylbutane-1,2-diyl]diphenol, ... (4 entities in total) |
Functional Keywords | estrogen agonist, breast cancer, nuclear hormone receptor, nuclear protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 62395.62 |
Authors | Fanning, S.W.,Han, R.,Maximov, P.,Jordan, V.C.,Greene, G.L. (deposition date: 2018-04-09, release date: 2019-03-20, Last modification date: 2023-10-04) |
Primary citation | Fanning, S.W. Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Z2OHTPE and a glucocorticoid receptor-interacting protein 1 NR box II peptide To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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