6CYF

PcrV fragment with bound Fab

Summary for 6CYF

Entry DOI	10.2210/pdb6cyf/pdb
Descriptor	Type III secretion system protein, IgG1 antibody, kappa light chain, IgG1 antibody, heavy chain fragment, ... (4 entities in total)
Functional Keywords	part of type 3 secretion system in pseudomonas aeruginosa, immune system
Biological source	Pseudomonas aeruginosa More
Total number of polymer chains	12
Total formula weight	246318.54
Authors	Oganesyan, V. (deposition date: 2018-04-05, release date: 2018-08-01, Last modification date: 2023-10-04)
Primary citation	Tabor, D.E.,Oganesyan, V.,Keller, A.E.,Yu, L.,McLaughlin, R.E.,Song, E.,Warrener, P.,Rosenthal, K.,Esser, M.,Qi, Y.,Ruzin, A.,Stover, C.K.,DiGiandomenico, A. Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates. J. Infect. Dis., 218:1983-1994, 2018 Cited by PubMed: 30016475 DOI: 10.1093/infdis/jiy438 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation