6CWG

Ricin catalytic subunit bound go A9 VHH antibody

Summary for 6CWG

DescriptorRicin, VHH antibody, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsricin catalytic subunit, vhh antibody, immune system
Biological sourceRicinus communis (Castor bean)
More
Total number of polymer chains4
Total molecular weight89639.71
Authors
Rudolph, M.J.,Mantis, N. (deposition date: 2018-03-30, release date: 2019-01-16)
Primary citation
Rudolph, M.J.,Vance, D.J.,Kelow, S.,Angalakurthi, S.K.,Nguyen, S.,Davis, S.A.,Rong, Y.,Middaugh, C.R.,Weis, D.D.,Dunbrack Jr., R.,Karanicolas, J.,Mantis, N.J.
Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.
Protein Eng. Des. Sel., 31:277-287, 2018
PubMed: 30265352 (PDB entries with the same primary citation)
DOI: 10.1093/protein/gzy022
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26880 1.7% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6cwg
no rotation
Molmil generated image of 6cwg
rotated about x axis by 90°
Molmil generated image of 6cwg
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6cwg
no rotation
Molmil generated image of 6cwg
rotated about x axis by 90°
Molmil generated image of 6cwg
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6cwg.pdb1.gz [132.51 KB])
Coordinate files for Biological unit (6cwg.pdb2.gz [131.47 KB])
PDBj@FacebookPDBj@TwitterwwPDBwwPDB Foundation

Copyright © 2013-2019 Protein Data Bank Japan