6CUT

Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine

6CUT の概要

• エントリーDOI: 10.2210/pdb6cut/pdb
• 分子名称: Tryptophan synthase beta chain 1, (2S,3S)-3-hydroxy-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-methylpentanoic acid (non-preferred name), SODIUM ION, ... (4 entities in total)
• 機能のキーワード: external aldimine, (2s, 3s)-isopropylserine, lyase
• 由来する生物種: Pyrococcus furiosus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 171042.95

構造登録者

Boville, C.E.,Scheele, R.A.,Buller, A.R.,Arnold, F.H. (登録日: 2018-03-26, 公開日: 2018-09-26, 最終更新日: 2024-03-13)

• 主引用文献: Boville, C.E.,Scheele, R.A.,Koch, P.,Brinkmann-Chen, S.,Buller, A.R.,Arnold, F.H.; Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues.; Angew. Chem. Int. Ed. Engl., 57:14764-14768, 2018; PubMed: 30215880; DOI: 10.1002/anie.201807998

実験手法

X-RAY DIFFRACTION (1.77 Å)