Crystal structure of the unliganded BC8B TCR

Summary for 6CUH

DescriptorT-cell Receptor alpha variable, TRAV 9-2. BC8B TCR, T-cell Receptor beta variable, TRBV 6-2. BC8B TCR, DI(HYDROXYETHYL)ETHER, ... (7 entities in total)
Functional Keywordst cell receptor, tcr, bc8b, cd1b, pc, phosphatidylcholine, immune system
Biological sourceHomo sapiens
Total number of polymer chains2
Total molecular weight50647.18
Shahine, A.E.,Rossjohn, J. (deposition date: 2018-03-26, release date: 2019-01-16)
Primary citation
Shahine, A.,Reinink, P.,Reijneveld, J.F.,Gras, S.,Holzheimer, M.,Cheng, T.Y.,Minnaard, A.J.,Altman, J.D.,Lenz, S.,Prandi, J.,Kubler-Kielb, J.,Moody, D.B.,Rossjohn, J.,Van Rhijn, I.
A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids.
Nat Commun, 10:56-56, 2019
PubMed: 30610190 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-07898-0
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2466 0.2% 2.6% 2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6cuh
no rotation
Molmil generated image of 6cuh
rotated about x axis by 90°
Molmil generated image of 6cuh
rotated about y axis by 90°
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