6CU7

Alpha Synuclein fibril formed by full length protein - Rod Polymorph

Summary for 6CU7

Entry DOI	10.2210/pdb6cu7/pdb
EMDB information	7618
Descriptor	Alpha-synuclein (1 entity in total)
Functional Keywords	parkinson's disease, synucleinopathy, amyloid aggregation, fibril polymorphism, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	10
Total formula weight	144761.08
Authors	Li, B.,Hatami, A.,Ge, P.,Murray, K.A.,Sheth, P.,Zhang, M.,Nair, G.,Sawaya, M.R.,Zhu, C.,Broad, M.,Shin, W.S.,Ye, S.,John, V.,Eisenberg, D.S.,Zhou, Z.H.,Jiang, L. (deposition date: 2018-03-23, release date: 2018-09-12, Last modification date: 2024-03-13)
Primary citation	Li, B.,Ge, P.,Murray, K.A.,Sheth, P.,Zhang, M.,Nair, G.,Sawaya, M.R.,Shin, W.S.,Boyer, D.R.,Ye, S.,Eisenberg, D.S.,Zhou, Z.H.,Jiang, L. Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9:3609-3609, 2018 Cited by PubMed: 30190461 DOI: 10.1038/s41467-018-05971-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation