6CSQ
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with cyclohexylhydroxamate
Summary for 6CSQ
Entry DOI | 10.2210/pdb6csq/pdb |
Descriptor | Hdac6 protein, ZINC ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | zinc hydrolase, tubulin deacetylase, hydrolase |
Biological source | Danio rerio (Zebrafish) |
Total number of polymer chains | 2 |
Total formula weight | 81144.55 |
Authors | Porter, N.J.,Christianson, D.W. (deposition date: 2018-03-21, release date: 2018-05-30, Last modification date: 2024-03-13) |
Primary citation | Porter, N.J.,Wagner, F.F.,Christianson, D.W. Entropy as a Driver of Selectivity for Inhibitor Binding to Histone Deacetylase 6. Biochemistry, 57:3916-3924, 2018 Cited by PubMed: 29775292DOI: 10.1021/acs.biochem.8b00367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.031 Å) |
Structure validation
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