6CRX

SARS Spike Glycoprotein, Stabilized variant, two S1 CTDs in the upwards conformation

6CRX の概要

• エントリーDOI: 10.2210/pdb6crx/pdb
• EMDBエントリー: 7575
• 分子名称: Spike glycoprotein,Fibritin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: membrane fusion, glycoprotein, receptor binding, viral protein
• 由来する生物種: Human SARS coronavirus (SARS-CoV); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 419332.91

構造登録者

Kirchdoerfer, R.N.,Wang, N.,Pallesen, J.,Turner, H.L.,Cottrell, C.A.,McLellan, J.S.,Ward, A.B. (登録日: 2018-03-19, 公開日: 2018-04-11, 最終更新日: 2020-07-29)

• 主引用文献: Kirchdoerfer, R.N.,Wang, N.,Pallesen, J.,Wrapp, D.,Turner, H.L.,Cottrell, C.A.,Corbett, K.S.,Graham, B.S.,McLellan, J.S.,Ward, A.B.; Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.; Sci Rep, 8:15701-15701, 2018; PubMed: 30356097; DOI: 10.1038/s41598-018-34171-7

実験手法

ELECTRON MICROSCOPY (3.9 Å)