6CO3

aducanumab abeta complex

Summary for 6CO3

• Entry DOI: 10.2210/pdb6co3/pdb
• Descriptor: Fab light chain, Fab heavy chain, ALA-GLU-PHE-ARG-HIS-ASP, ... (5 entities in total)
• Functional Keywords: antibody fab fragment, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 49026.63

Authors

Arndt, J.W. (deposition date: 2018-03-10, release date: 2018-05-02, Last modification date: 2023-10-04)

• Primary citation: Arndt, J.W.,Qian, F.,Smith, B.A.,Quan, C.,Kilambi, K.P.,Bush, M.W.,Walz, T.,Pepinsky, R.B.,Bussiere, T.,Hamann, S.,Cameron, T.O.,Weinreb, P.H.; Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-beta.; Sci Rep, 8:6412-6412, 2018; PubMed: 29686315; DOI: 10.1038/s41598-018-24501-0

Experimental method

X-RAY DIFFRACTION (2.384 Å)