6CO2
Structure of an engineered protein (NUDT16TI) in complex with 53BP1 Tudor domains
Summary for 6CO2
Entry DOI | 10.2210/pdb6co2/pdb |
Related | 6CO1 |
Descriptor | NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1 (3 entities in total) |
Functional Keywords | designer protein, engineered protein, nudt16ti, nudt16, 53bp1, tirr, tudor domain, rna binding, protein binding, rna nucleotide diphosphatase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 70970.90 |
Authors | Botuyan, M.V.,Thompson, J.R.,Cui, G.,Mer, G. (deposition date: 2018-03-10, release date: 2018-06-06, Last modification date: 2023-10-04) |
Primary citation | Botuyan, M.V.,Cui, G.,Drane, P.,Oliveira, C.,Detappe, A.,Brault, M.E.,Parnandi, N.,Chaubey, S.,Thompson, J.R.,Bragantini, B.,Zhao, D.,Chapman, J.R.,Chowdhury, D.,Mer, G. Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25:591-600, 2018 Cited by PubMed: 29967538DOI: 10.1038/s41594-018-0083-z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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