6CM4
Structure of the D2 Dopamine Receptor Bound to the Atypical Antipsychotic Drug Risperidone
Replaces: 6C38Summary for 6CM4
Entry DOI | 10.2210/pdb6cm4/pdb |
Descriptor | D(2) dopamine receptor, endolysin chimera, 3-[2-[4-(6-fluoranyl-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
Functional Keywords | gpcr, d2, dopamine receptor, antipsychotic, risperidone, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 50455.63 |
Authors | Wang, S.,Che, T.,Levit, A.,Shoichet, B.K.,Wacker, D.,Roth, B.L. (deposition date: 2018-03-02, release date: 2018-03-14, Last modification date: 2023-10-04) |
Primary citation | Wang, S.,Che, T.,Levit, A.,Shoichet, B.K.,Wacker, D.,Roth, B.L. Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone. Nature, 555:269-273, 2018 Cited by PubMed: 29466326DOI: 10.1038/nature25758 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.867 Å) |
Structure validation
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