6CLW
Crystal structure of TnmH
Summary for 6CLW
| Entry DOI | 10.2210/pdb6clw/pdb |
| Descriptor | O-methyltransferase (2 entities in total) |
| Functional Keywords | methyltransferase, biosynthetic protein |
| Biological source | Streptomyces sp. CB03234 |
| Total number of polymer chains | 2 |
| Total formula weight | 77133.75 |
| Authors | Chang, C.Y.,Annaval, T.,Adhikari, A.,Yan, X.,Shen, B. (deposition date: 2018-03-02, release date: 2019-03-06, Last modification date: 2023-10-04) |
| Primary citation | Adhikari, A.,Teijaro, C.N.,Yan, X.,Chang, C.Y.,Gui, C.,Liu, Y.C.,Crnovcic, I.,Yang, D.,Annaval, T.,Rader, C.,Shen, B. Characterization of TnmH as anO-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates. J.Med.Chem., 63:8432-8441, 2020 Cited by PubMed: 32658465DOI: 10.1021/acs.jmedchem.0c00799 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.74 Å) |
Structure validation
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