6CLW

Crystal structure of TnmH

6CLW の概要

• エントリーDOI: 10.2210/pdb6clw/pdb
• 分子名称: O-methyltransferase (2 entities in total)
• 機能のキーワード: methyltransferase, biosynthetic protein
• 由来する生物種: Streptomyces sp. CB03234
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 77133.75

構造登録者

Chang, C.Y.,Annaval, T.,Adhikari, A.,Yan, X.,Shen, B. (登録日: 2018-03-02, 公開日: 2019-03-06, 最終更新日: 2023-10-04)

• 主引用文献: Adhikari, A.,Teijaro, C.N.,Yan, X.,Chang, C.Y.,Gui, C.,Liu, Y.C.,Crnovcic, I.,Yang, D.,Annaval, T.,Rader, C.,Shen, B.; Characterization of TnmH as anO-Methyltransferase Revealing Insights into Tiancimycin Biosynthesis and Enabling a Biocatalytic Strategy To Prepare Antibody-Tiancimycin Conjugates.; J.Med.Chem., 63:8432-8441, 2020; PubMed: 32658465; DOI: 10.1021/acs.jmedchem.0c00799

実験手法

X-RAY DIFFRACTION (2.74 Å)