6CKN
Crystal structure of an AF10 fragment
Summary for 6CKN
Entry DOI | 10.2210/pdb6ckn/pdb |
Descriptor | Protein AF-10, UNKNOWN ATOM OR ION (2 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, dna binding protein |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : P55197 |
Total number of polymer chains | 2 |
Total formula weight | 17583.63 |
Authors | Qin, S.,Tempel, W.,Li, Y.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-02-28, release date: 2018-03-21, Last modification date: 2018-04-18) |
Primary citation | Zhang, H.,Zhou, B.,Qin, S.,Xu, J.,Harding, R.,Tempel, W.,Nayak, V.,Li, Y.,Loppnau, P.,Dou, Y.,Min, J. Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis. Genes Dev., 32:341-346, 2018 Cited by PubMed: 29563185DOI: 10.1101/gad.311639.118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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