6CJS
Candida albicans Hsp90 nucleotide binding domain in complex with AUY922
Summary for 6CJS
Entry DOI | 10.2210/pdb6cjs/pdb |
Related | 6CJI 6CJJ 6CJL 6CJP 6CJR |
Descriptor | Heat shock protein 90 homolog, 5-[2,4-DIHYDROXY-5-(1-METHYLETHYL)PHENYL]-N-ETHYL-4-[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ISOXAZOLE-3-CARBOXAMIDE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | hsp90. atpase, chaperone |
Biological source | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Total number of polymer chains | 1 |
Total formula weight | 26736.25 |
Authors | Kirkpatrick, M.G.,Pizarro, J.C. (deposition date: 2018-02-26, release date: 2019-01-30, Last modification date: 2023-10-04) |
Primary citation | Whitesell, L.,Robbins, N.,Huang, D.S.,McLellan, C.A.,Shekhar-Guturja, T.,LeBlanc, E.V.,Nation, C.S.,Hui, R.,Hutchinson, A.,Collins, C.,Chatterjee, S.,Trilles, R.,Xie, J.L.,Krysan, D.J.,Lindquist, S.,Porco Jr., J.A.,Tatu, U.,Brown, L.E.,Pizarro, J.,Cowen, L.E. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nat Commun, 10:402-402, 2019 Cited by PubMed: 30679438DOI: 10.1038/s41467-018-08248-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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