6CHD

Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine

6CHD の概要

• エントリーDOI: 10.2210/pdb6chd/pdb
• 分子名称: Lysine--tRNA ligase, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: atp binding, aminoacylation, amino acid binding, atp adenylyltransferase activity, trna binding, ligase, transferase, structure-guided drug discovery consortium
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Isoform Cytoplasmic: Cytoplasm, cytosol . Isoform Mitochondrial: Mitochondrion : Q15046
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 138447.74

構造登録者

Dranow, D.M.,Abendroth, J.,Lorimer, D.D. (登録日: 2018-02-22, 公開日: 2018-03-07, 最終更新日: 2023-10-04)

• 主引用文献: Dranow, D.M.,Abendroth, J.,Baragana, B.,Walpole, C.,Lorimer, D.D.; Crystal Structure of Human Lysyl-tRNA Synthetase complexed with L-Lysylsulfamoyl Adenosine; to be published,

実験手法

X-RAY DIFFRACTION (2.5 Å)