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6CFP

CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE

Summary for 6CFP
Entry DOI10.2210/pdb6cfp/pdb
DescriptorUbiquitin-like protein SMT3,Polymerase acidic protein, 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywordsinfluenza, h1n1, fragment-based drug discovery, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
More
Total number of polymer chains1
Total formula weight64454.60
Authors
Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-02-15, release date: 2018-04-11, Last modification date: 2023-10-04)
Primary citationSeattle Structural Genomics Center for Infectious Disease (SSGCID),Davies, D.R.,Abendroth, J.,Lorimer, D.,Horanyi, P.S.,Edwards, T.E.
CRYSTAL STRUCTURE OF POLYMERASE ACID PROTEIN (PA) FROM INFLUENZA A VIRUS, WILSON-SMITH/1933 (H1N1) BOUND TO FRAGMENT HIT BSI-70565 1-{1-[4-FLUOROPHENYL)METHYL]-2-METHYL-1H-IMIDAZOL-4-YL}ETHAN-1-ONE
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

246031

数据于2025-12-10公开中

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