6CEZ

Crystal Structure of Rabbit Anti-HIV-1 gp120 V2 Fab 16C2 in complex with V2 peptide ConB

6CEZ の概要

• エントリーDOI: 10.2210/pdb6cez/pdb
• 分子名称: Light chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, Heavy chain of Fab fragment of rabbit anti-HIV1 gp120 V2 mAb 16C2, HIV-1 gp120 V2 Peptide Con B, ... (4 entities in total)
• 機能のキーワード: hiv, gp120, v2, antibody, immune system
• 由来する生物種: Oryctolagus cuniculus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 47607.77

構造登録者

Kong, X.,Pan, R. (登録日: 2018-02-13, 公開日: 2018-09-12, 最終更新日: 2019-12-18)

• 主引用文献: Lertjuthaporn, S.,Cicala, C.,Van Ryk, D.,Liu, M.,Yolitz, J.,Wei, D.,Nawaz, F.,Doyle, A.,Horowitch, B.,Park, C.,Lu, S.,Lou, Y.,Wang, S.,Pan, R.,Jiang, X.,Villinger, F.,Byrareddy, S.N.,Santangelo, P.J.,Morris, L.,Wibmer, C.K.,Biris, K.,Mason, R.D.,Gorman, J.,Hiatt, J.,Martinelli, E.,Roederer, M.,Fujikawa, D.,Gorini, G.,Franchini, G.,Arakelyan, A.,Ansari, A.A.,Pattanapanyasat, K.,Kong, X.P.,Fauci, A.S.,Arthos, J.; Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha 4 beta 7.; PLoS Pathog., 14:e1007278-e1007278, 2018; PubMed: 30153309; DOI: 10.1371/journal.ppat.1007278

実験手法

X-RAY DIFFRACTION (2.399 Å)