6CET

Cryo-EM structure of GATOR1

Summary for 6CET

• Entry DOI: 10.2210/pdb6cet/pdb
• EMDB information: 7465
• Descriptor: GATOR complex protein NPRL2, GATOR complex protein NPRL3, GATOR complex protein DEPDC5 (3 entities in total)
• Functional Keywords: mtorc1 amino-acid sensing lysosome growth control, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 288870.21

Authors

Shen, K.,Huang, R.K.,Brignole, E.J.,Yu, Z.,Sabatini, D.M. (deposition date: 2018-02-12, release date: 2018-03-28, Last modification date: 2024-03-13)

• Primary citation: Shen, K.,Huang, R.K.,Brignole, E.J.,Condon, K.J.,Valenstein, M.L.,Chantranupong, L.,Bomaliyamu, A.,Choe, A.,Hong, C.,Yu, Z.,Sabatini, D.M.; Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.; Nature, 556:64-69, 2018; PubMed: 29590090; DOI: 10.1038/nature26158

Experimental method

ELECTRON MICROSCOPY (4.4 Å)