6CEH
Design, Synthesis, X-ray and Biological Activities of Selenides Bearing the Benzenesulfonamide Moiety as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology
6CEH の概要
エントリーDOI | 10.2210/pdb6ceh/pdb |
分子名称 | Carbonic anhydrase 2, ZINC ION, 4-[(prop-2-en-1-yl)selanyl]benzene-1-sulfonamide, ... (6 entities in total) |
機能のキーワード | carbonic anhydrase inhibitors, diabetic pathology, organoselenium, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 30059.92 |
構造登録者 | Peat, T.S.,Angeli, A.,di Cesare Mannelli, L.,Trallori, E.,Ghelardini, C.,Carta, F.,Supuran, C.T. (登録日: 2018-02-11, 公開日: 2018-05-23, 最終更新日: 2023-10-04) |
主引用文献 | Angeli, A.,di Cesare Mannelli, L.,Trallori, E.,Peat, T.S.,Ghelardini, C.,Carta, F.,Supuran, C.T. Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology. ACS Med Chem Lett, 9:462-467, 2018 Cited by PubMed: 29795760DOI: 10.1021/acsmedchemlett.8b00076 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.43 Å) |
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