6CDE

Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122

6CDE の概要

EMDBエントリーEMD-7459
分子名称vFP20.01 Heavy Chain, vFP20.01 Light chain, PGT122 Heavy chain, ... (11 entities in total)
機能のキーワードhiv-1 env, bg505 sosip, fusion peptide, vrc03, pgt122, vfp20.01, viral protein
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Host cell membrane ; Peripheral membrane protein . Surface protein gp120: Virion membrane ; Peripheral membrane protein . Transmembrane protein gp41: Virion membrane ; Single-pass type I membrane protein  Q2N0S7 Q2N0S5
ポリマー鎖数24
分子量合計679408.28
構造登録者
Acharya, P.,Xu, K.,Liu, K.,Carragher, B.,Potter, C.S.,Kwong, P.D. (登録日: 2018-02-08, 公開日: 2018-05-16)
主引用文献
Xu, K.,Acharya, P.,Carragher, B.,Potter, C.S.,Kwong, P.D.
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
to be published,
実験手法
ELECTRON MICROSCOPY (3.8 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliers601.5%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

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