6CBU

Crystal structure of C4S3: A computationally designed immunogen to target Carbohydrate-Occluded Epitopes on the HIV envelope

6CBU の概要

• エントリーDOI: 10.2210/pdb6cbu/pdb
• 分子名称: Acylphosphatase-1, SULFATE ION (3 entities in total)
• 機能のキーワード: immunogen, hiv-1, gp120, protein design, transport protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11402.77

構造登録者

Zhu, C.,Ke, H.M.,Swanstrom, R.,Dokholyan, N.V. (登録日: 2018-02-05, 公開日: 2019-02-06, 最終更新日: 2023-10-04)

• 主引用文献: Zhu, C.,Dukhovlinova, E.,Council, O.,Ping, L.,Faison, E.M.,Prabhu, S.S.,Potter, E.L.,Upton, S.L.,Yin, G.,Fay, J.M.,Kincer, L.P.,Spielvogel, E.,Campbell, S.L.,Benhabbour, S.R.,Ke, H.,Swanstrom, R.,Dokholyan, N.V.; Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies.; Nat Commun, 10:948-948, 2019; PubMed: 30814513; DOI: 10.1038/s41467-019-08876-w

実験手法

X-RAY DIFFRACTION (1.2 Å)