6C63
Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin
Summary for 6C63
Entry DOI | 10.2210/pdb6c63/pdb |
Descriptor | RNA (36-MER), RNA (32-MER), 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, ... (4 entities in total) |
Functional Keywords | fluorescent, rna, aptamer, g-quadruplex |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 36043.42 |
Authors | Trachman, R.J.,Ferre-D'Amare, A.R. (deposition date: 2018-01-17, release date: 2018-08-08, Last modification date: 2023-10-04) |
Primary citation | Trachman 3rd., R.J.,Abdolahzadeh, A.,Andreoni, A.,Cojocaru, R.,Knutson, J.R.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R. Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness. Biochemistry, 57:3544-3548, 2018 Cited by PubMed: 29768001DOI: 10.1021/acs.biochem.8b00399 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.90002801531 Å) |
Structure validation
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