6C63

Crystal Structure of the Mango-II Fluorescent Aptamer Bound to TO1-Biotin

6C63 の概要

• エントリーDOI: 10.2210/pdb6c63/pdb
• 分子名称: RNA (36-MER), RNA (32-MER), 4-[(3-{2-[(2-methoxyethyl)amino]-2-oxoethyl}-1,3-benzothiazol-3-ium-2-yl)methyl]-1-methylquinolin-1-ium, ... (4 entities in total)
• 機能のキーワード: fluorescent, rna, aptamer, g-quadruplex
• 由来する生物種: synthetic construct; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36043.42

構造登録者

Trachman, R.J.,Ferre-D'Amare, A.R. (登録日: 2018-01-17, 公開日: 2018-08-08, 最終更新日: 2023-10-04)

• 主引用文献: Trachman 3rd., R.J.,Abdolahzadeh, A.,Andreoni, A.,Cojocaru, R.,Knutson, J.R.,Ryckelynck, M.,Unrau, P.J.,Ferre-D'Amare, A.R.; Crystal Structures of the Mango-II RNA Aptamer Reveal Heterogeneous Fluorophore Binding and Guide Engineering of Variants with Improved Selectivity and Brightness.; Biochemistry, 57:3544-3548, 2018; PubMed: 29768001; DOI: 10.1021/acs.biochem.8b00399

実験手法

X-RAY DIFFRACTION (2.90002801531 Å)