6C2W
Crystal structure of human prothrombin mutant S101C/A470C
Summary for 6C2W
Entry DOI | 10.2210/pdb6c2w/pdb |
Descriptor | Prothrombin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | hydrolase, kringle, enzyme mechanism, coagulation factor, blood clotting |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 134120.52 |
Authors | Chinnaraj, M.,Chen, Z.,Pelc, L.,Grese, Z.,Bystranowska, D.,Di Cera, E.,Pozzi, N. (deposition date: 2018-01-09, release date: 2018-02-28, Last modification date: 2023-11-15) |
Primary citation | Chinnaraj, M.,Chen, Z.,Pelc, L.A.,Grese, Z.,Bystranowska, D.,Di Cera, E.,Pozzi, N. Structure of prothrombin in the closed form reveals new details on the mechanism of activation. Sci Rep, 8:2945-2945, 2018 Cited by PubMed: 29440720DOI: 10.1038/s41598-018-21304-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.12 Å) |
Structure validation
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