6C1W

A tethered niacin-derived pincer complex with a nickel-carbon or sulfite-carbon bond in lactate racemase

6C1W の概要

• エントリーDOI: 10.2210/pdb6c1w/pdb
• 分子名称: Lactate racemase, (4S)-5-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-4-sulfo-1,4-dihydropyridine-3-carbothioic S-acid, NICKEL (II) ION, ... (7 entities in total)
• 機能のキーワード: lar, nickel transferase, lara, nickel, lactate, lactate racemization, lactate racemase, sulfite, sulfite-bond, pincer, isomerase, cofactor
• 由来する生物種: Lactobacillus plantarum
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 145172.18

構造登録者

Fellner, M.,Desguin, B.,Hausinger, R.P.,Hu, J. (登録日: 2018-01-05, 公開日: 2018-03-14, 最終更新日: 2024-05-01)

• 主引用文献: Rankin, J.A.,Mauban, R.C.,Fellner, M.,Desguin, B.,McCracken, J.,Hu, J.,Varganov, S.A.,Hausinger, R.P.; Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism.; Biochemistry, 57:3244-3251, 2018; PubMed: 29489337; DOI: 10.1021/acs.biochem.8b00100

実験手法

X-RAY DIFFRACTION (2.398 Å)