6C1A
MBD2 in complex with methylated DNA
Summary for 6C1A
Entry DOI | 10.2210/pdb6c1a/pdb |
Descriptor | Methyl-CpG-binding domain protein 2, dna strand 1, complement to dna strand 1, ... (5 entities in total) |
Functional Keywords | dna methylation, dna binding, structural genomics, structural genomics consortium, sgc, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9UBB5 |
Total number of polymer chains | 8 |
Total formula weight | 49844.33 |
Authors | Liu, K.,Xu, C.,Tempel, W.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2018-01-04, release date: 2018-02-14, Last modification date: 2024-04-03) |
Primary citation | Liu, K.,Xu, C.,Lei, M.,Yang, A.,Loppnau, P.,Hughes, T.R.,Min, J. Structural basis for the ability of MBD domains to bind methyl-CG and TG sites in DNA. J. Biol. Chem., 293:7344-7354, 2018 Cited by PubMed: 29567833DOI: 10.1074/jbc.RA118.001785 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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