Summary for 6CD7
| Entry DOI | 10.2210/pdb6cd7/pdb |
| Descriptor | APH(2'')-Id, CHLORIDE ION, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro-2H-pyran-2-y l]oxy}-2-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide, ... (4 entities in total) |
| Functional Keywords | structural genomics, center for structural genomics of infectious diseases, csgid, eukaryotic protein kinase-like fold, aminoglycoside phosphotransferase, kinase, transferase, aminoglycosides, plazomicin, antibiotic, transferase-antibiotic complex, transferase/antibiotic |
| Biological source | Enterococcus casseliflavus (Enterococcus flavescens) |
| Total number of polymer chains | 2 |
| Total formula weight | 71699.42 |
| Authors | Stogios, P.J.,Evdokimova, E.,Dong, A.,Di Leo, R.,Savchenko, A.,Satchell, K.J.,Joachimiak, J.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2018-02-08, release date: 2018-02-28, Last modification date: 2023-10-04) |
| Primary citation | Cox, G.,Ejim, L.,Stogios, P.J.,Koteva, K.,Bordeleau, E.,Evdokimova, E.,Sieron, A.O.,Savchenko, A.,Serio, A.W.,Krause, K.M.,Wright, G.D. Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes. ACS Infect Dis, 4:980-987, 2018 Cited by PubMed: 29634241DOI: 10.1021/acsinfecdis.8b00001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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