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6C0A

Actinin-1 EF-Hand bound to the Cav1.2 IQ Motif

Summary for 6C0A
Entry DOI10.2210/pdb6c0a/pdb
NMR InformationBMRB: 25902
DescriptorAlpha-actinin-1, Voltage-dependent L-type calcium channel subunit alpha-1C (2 entities in total)
Functional Keywordsactinin-1, ef hand, calcium calmodulin, neuronal signaling, voltage gated calcium channel, cav1.2, voltage gated calcium channel 1.2, hippocampal neurons, iq motif, signaling protein
Biological sourceMus musculus (Mouse)
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Total number of polymer chains2
Total formula weight10769.13
Authors
Turner, M.L.,Ames, J.B. (deposition date: 2017-12-28, release date: 2019-01-16, Last modification date: 2023-06-14)
Primary citationTurner, M.L.,Anderson, D.E.,Coleman, A.,Horn, M.,Navedo, M.,Ames, J.B.,Hell, J.W.
Structural Basis of the Localization and Activation of Neuronal L-type Ca2+ Channels by a-Actinin1 and Calmodulin
To be Published,
Experimental method
SOLUTION NMR
Structure validation

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