Actinin-1 EF-Hand bound to the Cav1.2 IQ Motif

Summary for 6C0A

DescriptorAlpha-actinin-1, Voltage-dependent L-type calcium channel subunit alpha-1C (2 entities in total)
Functional Keywordsactinin-1, ef hand, calcium calmodulin, neuronal signaling, voltage gated calcium channel, cav1.2, voltage gated calcium channel 1.2, hippocampal neurons, iq motif, signaling protein
Biological sourceMus musculus (Mouse)
Total number of polymer chains2
Total molecular weight10769.13
Turner, M.L.,Ames, J.B. (deposition date: 2017-12-28, release date: 2019-01-16)
Primary citation
Turner, M.L.,Anderson, D.E.,Coleman, A.,Horn, M.,Navedo, M.,Ames, J.B.,Hell, J.W.
Structural Basis of the Localization and Activation of Neuronal L-type Ca2+ Channels by a-Actinin1 and Calmodulin
To be Published,
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers4 3.6% 15.4%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 6c0a
no rotation
Molmil generated image of 6c0a
rotated about x axis by 90°
Molmil generated image of 6c0a
rotated about y axis by 90°
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