6C06
Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin
Summary for 6C06
| Entry DOI | 10.2210/pdb6c06/pdb |
| Related | 6BZO 6C04 6C05 |
| EMDB information | 7323 |
| Descriptor | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (9 entities in total) |
| Functional Keywords | initiation, antibiotic, switch region inhibitor, transcription, transcription-antibiotic complex, transcription/antibiotic |
| Biological source | Mycobacterium tuberculosis More |
| Cellular location | Cytoplasm : A0A045HD00 |
| Total number of polymer chains | 7 |
| Total formula weight | 437917.00 |
| Authors | Darst, S.A.,Campbell, E.A.,Boyaci Selcuk, H.,Chen, J.,Lilic, M. (deposition date: 2017-12-27, release date: 2018-03-28, Last modification date: 2024-03-13) |
| Primary citation | Boyaci, H.,Chen, J.,Lilic, M.,Palka, M.,Mooney, R.A.,Landick, R.,Darst, S.A.,Campbell, E.A. Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7:-, 2018 Cited by PubMed: 29480804DOI: 10.7554/eLife.34823 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (5.15 Å) |
Structure validation
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