6BZV
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3
Summary for 6BZV
Entry DOI | 10.2210/pdb6bzv/pdb |
Descriptor | 19B3 GL Heavy Chain, 19B3 GL Light Chain, E2 AS412 peptide, ... (4 entities in total) |
Functional Keywords | hepatitis c virus, immune system, antibodies, broadly neutralizing antibodies, rational vaccine design, as412, e2, viral protein |
Biological source | Mus musculus More |
Total number of polymer chains | 12 |
Total formula weight | 197718.75 |
Authors | Tzarum, N.,Aleman, F.,Wilson, I.A.,Law, M. (deposition date: 2017-12-26, release date: 2018-06-20, Last modification date: 2022-02-02) |
Primary citation | Aleman, F.,Tzarum, N.,Kong, L.,Nagy, K.,Zhu, J.,Wilson, I.A.,Law, M. Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proc. Natl. Acad. Sci. U.S.A., 115:7569-7574, 2018 Cited by PubMed: 29954862DOI: 10.1073/pnas.1802378115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.654 Å) |
Structure validation
Download full validation report