6BZV

Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the GL precursor of the broadly neutralizing antibody 19B3

6BZV の概要

• エントリーDOI: 10.2210/pdb6bzv/pdb
• 分子名称: 19B3 GL Heavy Chain, 19B3 GL Light Chain, E2 AS412 peptide, ... (4 entities in total)
• 機能のキーワード: hepatitis c virus, immune system, antibodies, broadly neutralizing antibodies, rational vaccine design, as412, e2, viral protein
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 197718.75

構造登録者

Tzarum, N.,Aleman, F.,Wilson, I.A.,Law, M. (登録日: 2017-12-26, 公開日: 2018-06-20, 最終更新日: 2022-02-02)

• 主引用文献: Aleman, F.,Tzarum, N.,Kong, L.,Nagy, K.,Zhu, J.,Wilson, I.A.,Law, M.; Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.; Proc. Natl. Acad. Sci. U.S.A., 115:7569-7574, 2018; PubMed: 29954862; DOI: 10.1073/pnas.1802378115

実験手法

X-RAY DIFFRACTION (2.654 Å)