6BYU

X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex

6BYU の概要

• エントリーDOI: 10.2210/pdb6byu/pdb
• 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
• 機能のキーワード: rna polymerase, ppapp, escherichia coli x-ray structure, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Escherichia coli ; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 921340.18

構造登録者

Murakami, K.S.,Molodtsov, V. (登録日: 2017-12-21, 公開日: 2018-01-17, 最終更新日: 2023-10-04)

• 主引用文献: Bruhn-Olszewska, B.,Molodtsov, V.,Sobala, M.,Dylewski, M.,Murakami, K.S.,Cashel, M.,Potrykus, K.; Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro.; Biochim. Biophys. Acta, 1861:731-742, 2018; PubMed: 30012465; DOI: 10.1016/j.bbagrm.2018.07.005

実験手法

X-RAY DIFFRACTION (3.6 Å)