6BUB

Crystal structure of the PI3KC2alpha PX domain in space group P432

Summary for 6BUB

Entry DOI	10.2210/pdb6bub/pdb
Related	2IWL 6BTY 6BTZ 6BU0
Descriptor	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	px domain, lipid binding, phosphoinositide, pi3-kinase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	16926.38
Authors	Chen, K.-E.,Collins, B.M. (deposition date: 2017-12-09, release date: 2018-10-17, Last modification date: 2023-10-04)
Primary citation	Chen, K.E.,Tillu, V.A.,Chandra, M.,Collins, B.M. Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha. Structure, 26:1612-, 2018 Cited by PubMed: 30293811 DOI: 10.1016/j.str.2018.08.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.604 Å)

Structure validation