6BSI
Structure of HIV-1 RT complexed with an RNA/DNA hybrid containing the polypurine-tract sequence
Summary for 6BSI
Entry DOI | 10.2210/pdb6bsi/pdb |
Descriptor | REVERSE TRANSCRIPTASE P66 SUBUNIT, REVERSE TRANSCRIPTASE P51 SUBUNIT, DNA (5'-D(*GP*TP*TP*TP*TP*TP*CP*TP*TP*TP*TP*GP*TP*TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3'), ... (8 entities in total) |
Functional Keywords | hiv-rt, dna-rna complex, rnase h, viral protein, viral protein-dna-rna complex, viral protein-dna-rna-inhibitor complex, viral protein/dna/rna/inhibitor |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 4 |
Total formula weight | 131111.91 |
Authors | |
Primary citation | Tian, L.,Kim, M.S.,Li, H.,Wang, J.,Yang, W. Structure of HIV-1 reverse transcriptase cleaving RNA in an RNA/DNA hybrid. Proc. Natl. Acad. Sci. U.S.A., 115:507-512, 2018 Cited by PubMed: 29295939DOI: 10.1073/pnas.1719746115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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